Podocytic Infolding Glomerulopathy in a Patient with Phospholipase A2 Receptor-Positive Membranous Nephropathy and Review of the Literature

• Published in: Nephron (2015) Vol. 145; no. 5; p. 496
• Main Authors: Pandit, Amar P, Rennke, Helmut G, Denker, Bradley M
• Format: Journal Article
• Language: English
• Published: Switzerland 2021
• Subjects: Female; Glomerulonephritis, Membranous - diagnosis; Glomerulonephritis, Membranous - drug therapy; Glomerulonephritis, Membranous - enzymology; Glomerulonephritis, Membranous - pathology; Humans; Kidney Glomerulus - pathology; Kidney Glomerulus - ultrastructure; Microscopy, Electron; Middle Aged; Podocytes - pathology; Receptors, Phospholipase A2 - metabolism; Rituximab - therapeutic use; Rituximab; Antiphospholipid A2 receptor antibodies; Membranous nephropathy; Podocytic infolding

Podocytic infolding glomerulopathy (PIG) is a rare diagnosis based on characteristic histopathologic findings on renal biopsy and was proposed as a new entity about a decade ago. It is a type of podocytic injury, characterized by invagination of the podocyte cell membrane (cytoplasmic projections fr...