Host-microbiota interactions in the intestine

• Published in: Digestive diseases (Basel) Vol. 33; no. 2; p. 131
• Main Authors: Elson, Charles O, Alexander, Katie L
• Format: Journal Article
• Language: English
• Published: Switzerland 01.01.2015
• Subjects: Adaptive Immunity; Animals; Gastrointestinal Microbiome - immunology; Humans; Immunity, Innate; Intestinal Mucosa - immunology; Intestinal Mucosa - microbiology; Intestines - immunology; Intestines - microbiology; Lymphocytes - metabolism

The comprehensive collection of bacterial species, termed microbiota, within human and other mammalian hosts has profound effects on both innate and adaptive immunity. Multiple host innate mechanisms contribute to intestinal homeostasis, including epithelial production of protective mucin layers mai...