THE SCREENING AND RANKING ALGORITHM TO DETECT DNA COPY NUMBER VARIATIONS

• Published in: The annals of applied statistics Vol. 6; no. 3; p. 1306
• Main Authors: Niu, Yue S, Zhang, Heping
• Format: Journal Article
• Language: English
• Published: United States 01.09.2012
• Subjects: Change-point detection; high dimensional data; copy number variations; screening and ranking algorithm

DNA Copy number variation (CNV) has recently gained considerable interest as a source of genetic variation that likely influences phenotypic differences. Many statistical and computational methods have been proposed and applied to detect CNVs based on data that generated by genome analysis platforms...