Inhaled Nitric Oxide Therapy in the Post-Acute Phase in Extremely Preterm Infants: A Japanese Cohort Study

• Published in: The Journal of pediatrics Vol. 252; pp. 61 - 67.e5
• Main Authors: Nakanishi, Hidehiko, Isayama, Tetsuya, Kokubo, Masayo, Hirano, Shinya, Kusuda, Satoshi
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.01.2023
• Subjects: Administration, Inhalation; bronchopulmonary dysplasia; Bronchopulmonary Dysplasia - drug therapy; Cohort Studies; East Asian People; extremely preterm infants; Female; Humans; Infant; Infant, Extremely Premature; Infant, Newborn; Nitric Oxide - therapeutic use; Pregnancy; PPHN; NRNJ; extremely preterm infants; BPD; NICU; iNO; bronchopulmonary dysplasia

To determine the trends in inhaled nitric oxide (iNO) utilization in the late phase of hospitalization in a large Japanese cohort of extremely preterm infants and evaluate its benefit on long-term outcomes. This was a retrospective multicenter cohort study of 15 977 extremely preterm infants born at...