Mesenchymal Stromal Cell Secretome for Therapeutic Application in Skin Wound Healing: A Systematic Review of Preclinical Studies

• Published in: Cells, tissues, organs Vol. 212; no. 6; p. 567
• Main Authors: Marques da Silva, Maiara, Olsson, Débora Cristina, Teixeira, Bianca Luise, Jeremias, Talita da Silva, Trentin, Andrea Gonçalves
• Format: Journal Article
• Language: English
• Published: Switzerland 01.12.2023
• Subjects: Animals; Collagen; Endothelial Cells; Mesenchymal Stem Cell Transplantation - methods; Mesenchymal Stem Cells; Mice; Rats; Secretome; Skin - injuries; Wound Healing; Secretory vesicles; Animal studies; Wound healing; Conditioned media; Mesenchymal stem cells

Non-healing skin wounds remain a challenge in the healthcare system. In this sense, it is suggested that the secretome of mesenchymal stromal cells (MSCs) can be effective as a therapeutic strategy for regenerative medicine. Therefore, this systematic review aimed to determine the effects of treatme...