Molecular Simulation: a remarkable tool to study mechanisms of cell membrane preservation in probiotic bacteria
Molecular dynamics (MD) simulations have come of age. They have been increasingly used by scientists and engineers over the last two decades, and have attracted attention also in the field of food science, namely to address topics involving enzymes, carbohydrates, or cryoprotectants. This review foc...
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Published in | Current opinion in food science Vol. 50; p. 100985 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
Elsevier Ltd
01.04.2023
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Online Access | Get full text |
ISSN | 2214-7993 2214-8000 |
DOI | 10.1016/j.cofs.2022.100985 |
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Abstract | Molecular dynamics (MD) simulations have come of age. They have been increasingly used by scientists and engineers over the last two decades, and have attracted attention also in the field of food science, namely to address topics involving enzymes, carbohydrates, or cryoprotectants. This review focuses on the latter topic, more specifically on the application of MD to the study of lactic acid bacteria (cryo)preservation and the protective action operated by fructo-oligosaccharides. The lack of fundamental research on the subject and possible ways of filling this gap are discussed. |
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AbstractList | Molecular dynamics (MD) simulations have come of age. They have been increasingly used by scientists and engineers over the last two decades, and have attracted attention also in the field of food science, namely to address topics involving enzymes, carbohydrates, or cryoprotectants. This review focuses on the latter topic, more specifically on the application of MD to the study of lactic acid bacteria (cryo)preservation and the protective action operated by fructo-oligosaccharides. The lack of fundamental research on the subject and possible ways of filling this gap are discussed. |
ArticleNumber | 100985 |
Author | Gomez-Zavaglia, Andrea Simões, Pedro N Ureta, Micaela Ferreira, Tiago H Maximiano, Pedro |
Author_xml | – sequence: 1 givenname: Tiago H surname: Ferreira fullname: Ferreira, Tiago H organization: University of Coimbra, CIEPQPF, Department of Chemical Engineering, Rua Sílvio de Lima, Pólo II, 3030-790 Coimbra, Portugal – sequence: 2 givenname: Pedro surname: Maximiano fullname: Maximiano, Pedro organization: University of Coimbra, CIEPQPF, Department of Chemical Engineering, Rua Sílvio de Lima, Pólo II, 3030-790 Coimbra, Portugal – sequence: 3 givenname: Micaela surname: Ureta fullname: Ureta, Micaela organization: Center for Research and Development in Food Cryotechnology (CIDCA, CCT-CONICET), La Plata 1900, Argentina – sequence: 4 givenname: Andrea surname: Gomez-Zavaglia fullname: Gomez-Zavaglia, Andrea organization: Center for Research and Development in Food Cryotechnology (CIDCA, CCT-CONICET), La Plata 1900, Argentina – sequence: 5 givenname: Pedro N surname: Simões fullname: Simões, Pedro N email: pnsim@eq.uc.pt organization: University of Coimbra, CIEPQPF, Department of Chemical Engineering, Rua Sílvio de Lima, Pólo II, 3030-790 Coimbra, Portugal |
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Cites_doi | 10.3390/nu14102038 10.1016/j.molliq.2020.113639 10.1021/jp402385d 10.1021/acs.jpclett.1c02451 10.3389/fnut.2019.00078 10.1016/j.cofs.2016.08.003 10.1038/s41575-021-00440-6 10.3390/membranes9010015 10.1080/10408398.2017.1341864 10.1016/j.fluid.2018.07.006 10.1038/nrm2330 10.1016/j.chemphyslip.2017.11.015 10.1021/ja505476c 10.1017/S0022029900004179 10.1016/j.molliq.2018.10.094 10.3389/fmicb.2017.01750 10.1039/C5CP02472B 10.1016/j.sbi.2020.08.006 10.1021/acs.langmuir.9b03086 10.1111/1541-4337.12406 10.1016/j.cofs.2019.11.003 10.1186/1475-2859-13-S1-S9 10.1073/pnas.1012516108 10.1021/acs.jpcb.1c02575 10.1063/5.0011346 10.1002/cphc.202000219 10.1080/08927022.2021.1907382 10.1016/j.foodres.2016.11.003 |
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Snippet | Molecular dynamics (MD) simulations have come of age. They have been increasingly used by scientists and engineers over the last two decades, and have... |
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SubjectTerms | cell membranes cryoprotectants food science fructooligosaccharides lactic acid molecular dynamics probiotics |
Title | Molecular Simulation: a remarkable tool to study mechanisms of cell membrane preservation in probiotic bacteria |
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