Swine dust causes intense airways inflammation in healthy subjects

• Published in: American journal of respiratory and critical care medicine Vol. 150; no. 4; p. 973
• Main Authors: Larsson, K A, Eklund, A G, Hansson, L O, Isaksson, B M, Malmberg, P O
• Format: Journal Article
• Language: English
• Published: United States 01.10.1994
• Subjects: Adult; Agricultural Workers' Diseases - blood; Agricultural Workers' Diseases - epidemiology; Agricultural Workers' Diseases - etiology; Air Pollutants, Occupational - adverse effects; Air Pollutants, Occupational - analysis; Animals; Bronchitis - blood; Bronchitis - epidemiology; Bronchitis - etiology; Bronchoalveolar Lavage Fluid - chemistry; Bronchoalveolar Lavage Fluid - cytology; Bronchoscopy; Dust - adverse effects; Dust - analysis; Endotoxins - adverse effects; Endotoxins - analysis; Humans; Male; Middle Aged; Statistics, Nonparametric; Swine; Time Factors

Fourteen healthy, nonsmoking subjects were exposed to swine dust while weighing pigs for 3 to 5 h in a swine-confinement building. All but one participant was previously unexposed to swine dust. Bronchoalveolar lavage (BAL) was performed and blood samples were drawn before and after exposure. Total...