The cardiovascular subtleties of testosterone on gender-affirming hormone therapy

• Published in: American journal of physiology. Heart and circulatory physiology Vol. 325; no. 1; pp. H30 - H53
• Main Authors: Santos, Jeimison D, Oliveira-Neto, José T, Tostes, Rita C
• Format: Journal Article
• Language: English
• Published: United States American Physiological Society 01.07.2023
• Subjects: Blood pressure; Blood vessels; Cardiovascular diseases; Cardiovascular System; Endocrine therapy; Female; Gender; Gender aspects; Gender Identity; Gender-affirming care; Gonadal Steroid Hormones; Health risks; Hemodynamics; Homeostasis; Hormone replacement therapy; Hormones; Humans; Hypertension; Injury prevention; Male; Secondary sexual characters; Sex hormones; Testosterone; Testosterone - adverse effects; Transgender Persons; immune system; PVAT; hypertension; oxidative stress; cardiovascular hypertrophy

The growing number of people who identify themselves as transgender has gained increased attention in recent years and will certainly impact personalized clinical practices and healthcare worldwide. Transgender and gender-nonconforming individuals frequently undergo gender-affirming hormone therapy...