Photodynamic therapy of human undifferentiated thyroid carcinoma-bearing nude mice using topical 5-aminolevulinic acid

• Published in: Photomedicine and laser surgery Vol. 23; no. 2; p. 206
• Main Authors: Al-Watban, Farouk A H, Zhang, X Y
• Format: Journal Article
• Language: English
• Published: United States 01.04.2005
• Subjects: Administration, Topical; Aminolevulinic Acid - pharmacology; Animals; Carcinoma - pathology; Carcinoma - therapy; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Photochemotherapy; Photosensitizing Agents - pharmacology; Thyroid Neoplasms - pathology; Thyroid Neoplasms - therapy; Time Factors

We determined and evaluated the effect of photodynamic therapy (PDT) using topical 5-aminolevulinic acid (ALA) cream in treating human undifferentiated thyroid carcinoma (UTC)-bearing nude mice. UTC constitutes almost 10% of thyroid cancers and shows a very poor response to chemotherapy. Today PDT w...