High neutrophil-lymphocyte ratio is not independently associated with worse survival or recurrence in patients with extremity soft tissue sarcoma

• Published in: Surgery Vol. 168; no. 4; pp. 760 - 767
• Main Authors: Strong, Erin A., Park, Sandra H., Ethun, Cecilia G., Chow, Bonnie, King, David, Bedi, Meena, Charlson, John, Mogal, Harveshp, Tsai, Susan, Christians, Kathleen, Tran, Thuy B., Poultsides, George, Grignol, Valerie, Howard, J. Harrison, Tseng, Jennifer, Roggin, Kevin K., Chouliaras, Konstantinos, Votanopoulos, Konstantinos, Cullinan, Darren, Fields, Ryan C., Gamblin, T. Clark, Cardona, Kenneth, Clarke, Callisia N.
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 01.10.2020

Soft tissue sarcomas are a heterogenous group of neoplasms without well-validated biomarkers. Cancer-related inflammation is a known driver of tumor growth and progression. Recent studies have implicated a high circulating neutrophil-lymphocyte ratio as a surrogate marker for the inflammatory tumor...