Magnetic Resonance Spectroscopy of Brain Metabolism in Fetuses With Congenital Heart Disease

• Published in: Journal of the American College of Cardiology Vol. 82; no. 16; pp. 1614 - 1623
• Main Authors: Andescavage, Nickie N., Pradhan, Subechhya, Gimovsky, Alexis C., Kapse, Kushal, Donofrio, Mary T., Cheng, Jenhao Jacob, Sharker, Yushuf, Wessel, David, du Plessis, Adre J., Limperopoulos, Catherine
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 17.10.2023
• Subjects: brain; congenital heart disease; fetus; magnetic resonance imaging; metabolites; proton magnetic resonance spectroscopy; magnetic resonance imaging; MRI; 1H MRS; SV(AO); Cho; UA; Cr; Ins; 2V(AO); congenital heart disease; GA; LME; MCA; brain; metabolites; proton magnetic resonance spectroscopy; Lac; NAA; TGA; TE; sI; PI; fetus; CHD; TR

Congenital heart disease (CHD) remains a significant risk factor for neurologic injury because altered fetal hemodynamics may be unable to support typical brain development during critical periods of growth and maturation. The primary objective was to assess differences in the cerebral biochemical p...