Consensus guidelines for high dose rate remote brachytherapy in cervical, endometrial, and endobronchial tumors

• Published in: International journal of radiation oncology, biology, physics Vol. 27; no. 5; pp. 1241 - 1244
• Main Authors: Nag, Subir, Abitbol, Andre A., Anderson, Lowell L., Blasko, John C., Flores, Albino, Harrison, Louis B., Hilaris, Basil S., Martinez, Alvaro A., Mehta, Minesh P., Nori, Dattatreyudu, Porter, Arthur, Rossman, Kent J., Speiser, Burton L., Stitt, Judith Anne, Nisar Syed, A.M., VikramM, B.
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.12.1993; Elsevier
• Subjects: Afterloading; Biological and medical sciences; Brachytherapy; Cancer; Cervix; Endobronchial; Endometrium; Guidelines; High dose rate; Lung; Medical sciences; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects); Remote-controlled; Technology. Biomaterials. Equipments. Material. Instrumentation; Therapy; Therapy; Endobronchial; Remote-controlled; Lung; Afterloading; Brachytherapy; Cervix; Endometrium; High dose rate; Guidelines; Cancer; Human; Lung disease; Carcinoma; Respiratory disease; Malignant tumor; Uterine cervix; Intracavitary radiotherapy; Dose rate; Bronchopulmonary; Recommendation; Female genital diseases; Radiation dose; Treatment; Uterine diseases; Bronchus disease; Female; Technique; Curietherapy; Uterine cervix diseases
• DOI: 10.1016/0360-3016(93)90549-B
• ISSN: 0360-3016

Purpose : A large number of medical centers have recently instituted the use of High Dose-Rate Afterloading Brachytherapy (HDRAB). There is wide variation in treatment regimens, techniques, and dosimetry being used and there are no national standard protocols or guidelines for optimal therapy. Methods and Materials : The Clinical Research Committee (CRC) of the American Endocurietherapy Society (AES) met to formulate consensus guidelines for HDRAB in cervical, endometrial, and endobronchial tumors. Conclusion : Each center is encouraged to follow a consistent treatment policy in a controlled fashion with complete documentation of treatment parameters and outcome including efficacy and morbidity. Until further clinical data becomes available, the linear quadratic model can be used as a guideline to formulate a new HDR regimen exercising caution when changing from a Low Dose Rate (LDR) to a HDRAB regimen. The treatments should be fractionated as much as practical to minimize long term morbidity. As more clinical data becomes available, the guidelines will mature and be updated by the Clinical Research Committee of the AES.