Comparative outcome analysis of ABO-incompatible and positive crossmatch renal transplantation: a single-center experience

• Published in: Transplantation Vol. 87; no. 12; p. 1889
• Main Authors: Padmanabhan, Anand, Ratner, Lloyd E, Jhang, Jeffrey S, Duong, Jimmy K, Markowitz, Glen S, Vasilescu, Elena R, Crew, Russell J, Schwartz, Joseph
• Format: Journal Article
• Language: English
• Published: United States 27.06.2009
• Subjects: ABO Blood-Group System; Adult; Aged; Autoantibodies - blood; Blood Group Incompatibility - epidemiology; Creatinine - blood; Drug Therapy, Combination; Female; Flow Cytometry; Graft Rejection - epidemiology; Graft Rejection - immunology; Histocompatibility Antigens Class I - immunology; Histocompatibility Antigens Class II - immunology; Humans; Immunosuppressive Agents - therapeutic use; Incidence; Kidney Transplantation - adverse effects; Kidney Transplantation - immunology; Kidney Transplantation - pathology; Male; Middle Aged; Retrospective Studies

ABO-incompatible (ABOi) and positive crossmatch (XM) renal transplants pose special immunologic challenges. It is important to compare outcomes, study resource utilization, and attempt to risk stratify patients in these higher risk transplant settings. We compared apheresis utilization and transplan...