HBV induced hepatocellular carcinoma and related potential immunotherapy

• Published in: Pharmacological research Vol. 159; p. 104992
• Main Authors: Jia, Liyang, Gao, Yanan, He, Yaowu, Hooper, John D., Yang, Pengyuan
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01.09.2020
• Subjects: Hepatitis B virus (HBV); Hepatocellular carcinoma (HCC); Immune checkpoint inhibitors; Immunotherapy; Immune checkpoint inhibitors; Hepatitis B virus (HBV); Immunotherapy; Hepatocellular carcinoma (HCC)

[Display omitted] Chronic infection of Hepatitis B virus (HBV) has long been recognized as a major risk factor in the initiation and development of hepatocellular carcinoma (HCC), contributing to over half the cases of HCC worldwide. Transformation of the liver with HBV infection to HCC mainly resul...