Higher Expression of Lympho-epithelial Kazal-type-Related Inhibitor-1 Fragments and Decreased Desquamation in the Lesional Skin of Nummular Eczema

• Published in: Acta dermato-venereologica Vol. 104; p. adv188636
• Main Authors: Montenegro, Sara Estefania, Oh, Jang-Hee, Suh, Joong Heon, Mun, Je-Ho, Chung, Jin Ho
• Format: Journal Article
• Language: English
• Published: Sweden Society for Publication of Acta Dermato-Venereologica 29.03.2024; Medical Journals Sweden
• Subjects: Corneodesmosin; Desmocollin-1; Desmoglein-1; Lympho-epithelial Kazal-type-related inhibitor; Nummular eczema; Original Report

Nummular eczema, a chronic dermatitis characterized by coin-shaped lesions, was first documented in 1857. However, its pathophysiological characteristics are still not well known. To investigate differences in the regulation of the desquamation process in the stratum corneum of lesional and nonlesio...