Synthesis of tetrahydrobenzo[b]pyran under catalysis of NH4Al(SO4)2·12H2O (Alum)

• Published in: Arabian journal of chemistry Vol. 10; no. S2; pp. S2213 - S2216
• Main Authors: Mohammadi, Ali A., Asghariganjeh, Mohammad R., Hadadzahmatkesh, Armin
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.05.2017; Elsevier
• Subjects: Aldehydes; Dimedone; Multi component reaction; NH4Al(SO4)2·12H2O (Alum); Tetrahydrobenzo[b]pyrans; Dimedone; Multi component reaction; NH4Al(SO4)2·12H2O (Alum); Tetrahydrobenzo[b]pyrans; Aldehydes

A simple and efficient one-pot synthesis of tetrahydrobenzo[b]pyrans from the three-component reaction between dimedone, aldehydes, and active methylene compounds using NH4Al(SO4)2·12H2O (Alum) as a catalyst at 80°C is described. The catalyst exhibits remarkable reactivity and is reusable.