Multiple Model Optimal Sampling Promotes Accurate Vancomycin Area-Under-the-Curve Estimation Using a Single Sample in Critically Ill Children - Downes, Kevin J; Sharova, Anna; Malone, Judith; Odom John, Audrey R; Zuppa, Athena F; Neely, Michael N (Therapeutic drug monitoring, 2025)
Keywords: Adolescent; Anti-Bacterial Agents - blood; Anti-Bacterial Agents - pharmacokinetics; Anti-Bacterial Agents - therapeutic use; Area Under Curve; Bayes Theorem; Child; Child, Preschool; Critical Illness; Drug Monitoring - methods; Female; Humans; Infant; Male; Models, Biological; Prospective Studies; Vancomycin - administration & dosage; Vancomycin - blood; Vancomycin - pharmacokinetics; Vancomycin - therapeutic use; limited sampling; Bayesian estimation; pediatric infectious diseases; sepsis; therapeutic drug monitoring