Platelets: Novel Biomaterials for Cancer Diagnosis and Therapeutic Delivery

• Published in: MedComm - Biomaterials and applications Vol. 4; no. 2
• Main Authors: Wang, Xin, Chen, Jie, Shi, Hubing
• Format: Journal Article
• Language: English
• Published: London John Wiley & Sons, Inc 01.06.2025; Wiley
• Subjects: Artificial intelligence; Biocompatibility; Biomarkers; Biomedical materials; Biopsy; Blood platelets; Cancer; circulating tumor cells; Circulatory system; diagnose; Drug delivery systems; Effectiveness; Extracellular vesicles; Medical diagnosis; Metabolism; Metastasis; Mitochondria; Nanomaterials; platelets; platelet‐based nanomaterials; Proteins; Shear stress; Standardization; Tumors; tumor‐educated platelets

ABSTRACT Platelets play a pivotal role in cancer detection and metastasis, serving both as novel liquid biopsy biomarkers and as versatile carriers in nanomedicine. Tumor‐educated platelets (TEPs) undergo molecular alterations influenced by the tumor microenvironment, with their RNA profiles—includi...