Sidechain structure-activity relationships of cyclobutane-based small molecule αvβ3 antagonists - Throup, Adam; Zraikat, Manar Saleh; Gordon, Andrew; Jafarinejad Soumehsaraei, Shohreh; Haase, Kathrin D; Patterson, Laurence H; Cooper, Patricia A; Hanlon, Katherine; Loadman, Paul M; Sutherland, Mark; Shnyder, Steven D; Sheldrake, Helen M (MedChemComm, 2024)
Keywords: Acids; Aspartic acid; Cancer; Carboxylic acids; Cell surface; Cyclobutane; Drug development; Drug discovery; Extracellular matrix; Glycine; In vivo methods and tests; Lead compounds; Molecular structure; Synthesis