Prognosis and personalized treatment prediction in TP53 -mutant hepatocellular carcinoma: an in silico strategy towards precision oncology

• Published in: Briefings in bioinformatics Vol. 22; no. 3
• Main Authors: Yang, Chen, Huang, Xiaowen, Li, Yan, Chen, Junfei, Lv, Yuanyuan, Dai, Shixue
• Format: Journal Article
• Language: English
• Published: 20.05.2021

TP53 mutation is one of the most common genetic changes in hepatocellular carcinoma (HCC). It is of great clinical significance to tailor specialized prognostication approach and to explore more therapeutic options for TP53-mutant HCCs. In this study, a total of 1135 HCC patients were retrospectivel...