Muscle-to-tumor crosstalk: The effect of exercise-induced myokine on cancer progression

• Published in: Biochimica et biophysica acta. Reviews on cancer Vol. 1877; no. 5; p. 188761
• Main Authors: Huang, Qianrui, Wu, Mengling, Wu, Xuyi, Zhang, Yiwen, Xia, Yong
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.09.2022
• Subjects: Cachexia; Cancer; Exercise; Muscle; Myokine; ALK; TAM; CNTF; MDSC; SPARC; TFPI-2; CDK; Exercise; Arg-1; Muscle; TNBC; RFS; IL-1ra; FST; rhIL-6; IL-15; IR; IGF-1; DOX; IL-8; EMT; p38 MAPK; bFGF; IL-6; Myokine; FNDC5; PDAC; MMP-2; CRF; MET; ERK; CRP; T2DM; MCP-1; UCP1; CT-1; WAT; HIIT; FOXO1; URP; CAFs; LTPA; BMI; FGF21; ACF; BDNF; Tregs; VEGF; GRP78; OSM; Cachexia; PIF; TME; rDNA; SLRP; SCC; REE; BAT; CLCF1; PDGF; ATM; GLUT4; HIIE; ATP; Cancer; DC

Physical exercise has gradually become a focus in cancer treatment due to its pronounced role in reducing cancer risk, enhancing therapeutic efficacy, and improving prognosis. In recent decades, skeletal muscles have been considered endocrine organs, exerting their biological functions via the endoc...