Microwave Assisted Synthesis and Antimicrobial Potential of Quinoline‐Based 4‐Hydrazide‐Hydrazone Derivatives

• Published in: Journal of heterocyclic chemistry Vol. 55; no. 1; pp. 302 - 312
• Main Authors: Ajani, Olayinka O., Iyaye, King T., Audu, Oluwatosin Y., Olorunshola, Shade J., Kuye, Alice O., Olanrewaju, Ifedolapo O.
• Format: Journal Article
• Language: English
• Published: HOBOKEN Wiley 01.01.2018; Wiley Subscription Services, Inc
• Subjects: Agar; Antiinfectives and antibacterials; Antimicrobial agents; Carboxylic acids; Chemistry; Chemistry, Organic; Fourier transforms; Hydrazones; Irradiation; Microorganisms; NMR; Nuclear magnetic resonance; Physical Sciences; Quinoline; Science & Technology; Synthesis; DESIGN; ACID; HYDRAZONE DERIVATIVES; ANTICANCER AGENTS

Quinoline is a benzo‐fused pyridine which is a therapeutically important heterocycle in medicinal chemistry research and new drug development. A series of 12 new hydrazide‐hydrazone motifs bearing quinoline core 4a–l was successfully synthesized by microwave irradiation technique. The synthesis invo...