Acquisition and Transmission of Streptococcus pneumoniae Are Facilitated during Rhinovirus Infection in Families with Children

• Published in: American journal of respiratory and critical care medicine Vol. 196; no. 9; pp. 1172 - 1180
• Main Authors: Karppinen, Sinikka, Teräsjärvi, Johanna, Auranen, Kari, Schuez-Havupalo, Linnea, Siira, Lotta, He, Qiushui, Waris, Matti, Peltola, Ville
• Format: Journal Article
• Language: English
• Published: United States American Thoracic Society 01.11.2017
• Subjects: Adolescent; Antigens; Bacterial infections; Child; Child, Preschool; Confidence intervals; Ear diseases; Families & family life; Family; Female; Genomes; Humans; Infant; Male; Parents & parenting; Picornaviridae Infections - complications; Pneumococcal Infections - complications; Pneumococcal Infections - transmission; Pneumonia; Polymerase Chain Reaction; Rhinovirus - pathogenicity; Streptococcus infections; Streptococcus pneumoniae - pathogenicity; Viruses; Working groups; respiratory tract infection; children; rhinovirus; viral–bacterial interaction; Streptococcus pneumoniae

Laboratory and clinical evidence suggests synergy between rhinoviruses and Streptococcus pneumoniae in the pathogenesis of respiratory tract infections. However, it is unclear whether rhinoviruses promote pneumococcal acquisition and transmission. To describe the impact of rhinovirus infection on th...