Knockout of SlALKBH2 weakens the DNA damage repair ability of tomato

• Published in: Plant science (Limerick) Vol. 319; p. 111266
• Main Authors: Tan, Tingting, Li, Yangyang, Tang, Boyan, Chen, Yating, Chen, Xinru, Xie, Qiaoli, Hu, Zongli, Chen, Guoping
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier B.V 01.06.2022
• Subjects: Alkylation lesions; deformation; DNA; DNA damage; DNA Damage - genetics; DNA repair; environmental DNA; Escherichia coli; Escherichia coli - genetics; Escherichia coli Proteins - genetics; eukaryotic cells; evolution; genes; hypersensitivity; leaves; Lycopersicon esculentum - genetics; methylation; Mixed Function Oxygenases - genetics; MMS; Mutagens; mutants; oxygenases; prokaryotic cells; SlALKBH2; Solanum lycopersicum; tomatoes; transcription (genetics); MMS; SlALKBH2; DNA repair; Solanum lycopersicum; Alkylation lesions

During the growth and evolution of plants, genomic DNA is subject to constant assault from endogenous and environmental DNA damage compounds, which will result in mutagenic or genotoxic covalent adducts. Whether for prokaryotes, eukaryotes or even viruses, maintaining genome integrity is critical fo...