Rapid onset of small intestinal perforation after successful steroid treatment in eosinophilic granulomatosis with polyangiitis
Eosinophilic granulomatosis with polyangiitis (EGPA) is a disorder characterized by extravascular granulomas, hypereosinophilia, and pulmonary and systemic small-vessel vasculitis. Bowel perforation is a rare but often fatal complication of EGPA. In the present report, we describe a case of small in...
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| Published in | Modern rheumatology Vol. 26; no. 6; pp. 968 - 970 |
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| Main Authors | , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
01.11.2016
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| Subjects | |
| Online Access | Get full text |
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| Abstract | Eosinophilic granulomatosis with polyangiitis (EGPA) is a disorder characterized by extravascular granulomas, hypereosinophilia, and pulmonary and systemic small-vessel vasculitis. Bowel perforation is a rare but often fatal complication of EGPA. In the present report, we describe a case of small intestinal perforation in a patient with EGPA. Through various examinations, we confirmed the presence of EGPA, and the patient responded well to steroid therapy. However, as the patient's condition subsequently worsened, the small intestine was consequently resected. The patient's overall condition improved thereafter. Thus, we believe that careful attention should be paid to intestinal symptoms and perforation in patients with EGPA. |
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| AbstractList | Eosinophilic granulomatosis with polyangiitis (EGPA) is a disorder characterized by extravascular granulomas, hypereosinophilia, and pulmonary and systemic small-vessel vasculitis. Bowel perforation is a rare but often fatal complication of EGPA. In the present report, we describe a case of small intestinal perforation in a patient with EGPA. Through various examinations, we confirmed the presence of EGPA, and the patient responded well to steroid therapy. However, as the patient's condition subsequently worsened, the small intestine was consequently resected. The patient's overall condition improved thereafter. Thus, we believe that careful attention should be paid to intestinal symptoms and perforation in patients with EGPA. |
| Author | Ikeda, Keigo Sekigawa, Iwao Takasaki, Yoshinari |
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| SubjectTerms | Adult Female Granulomatosis with Polyangiitis - complications Granulomatosis with Polyangiitis - drug therapy Humans Intestinal Perforation - etiology Steroids - therapeutic use |
| Title | Rapid onset of small intestinal perforation after successful steroid treatment in eosinophilic granulomatosis with polyangiitis |
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