Is the time right for in vitro neurotoxicity testing using human iPSC-derived neurons? - Tukker, Anke (ALTEX, 2016)
Keywords: Animals; Cell Differentiation; Cells, Cultured; Coculture Techniques; Electrophysiological Phenomena; Fluoroimmunoassay; Gene Expression Regulation - physiology; Humans; Induced Pluripotent Stem Cells - cytology; Induced Pluripotent Stem Cells - physiology; Ion Channels - physiology; Neurons - cytology; Neurons - physiology; Rats; Receptors, Neurotransmitter - genetics; Receptors, Neurotransmitter - metabolism; Staining and Labeling; Toxicity Tests - methods; alternatives to animal testing; multi-electrode array (MEA); mixed neuronal cultures; human induced pluripotent stem cell-derived neurons; in vitro neurotoxicity screening