Genetic assessment of the causal effect of plasma metabolites and metabolic pathways on delirium

• Published in: ANESTHESIOLOGY AND PERIOPERATIVE SCIENCE Vol. 2; no. 3; pp. 1 - 11
• Main Authors: He, Xin, Shi, XinYu, Wang, YiNi, Han, Shuang, Liu, JiaYan, Yang, Fei, Ma, Kun, Li, Bai-Xiang
• Format: Journal Article
• Language: English
• Published: Singapore Springer Nature Singapore 14.08.2024; Springer
• Subjects: Anesthesiology; Critical Care Medicine; Delirium; Genome-wide association study; Intensive; Medicine; Medicine & Public Health; Mendelian randomization; Neurosciences; Original Research; Pharmacology/Toxicology; Plasma metabolites; Surgery; Delirium; Plasma metabolites; Mendelian randomization; Genome-wide association study

Purpose Delirium has a significant impact on millions of people globally and is closely linked to an unfavorable prognosis for complications. Observational studies suggest that plasma metabolites may play significant roles as markers and effectors of delirium, but causal relationships have not yet b...