Aspergillus fumigatus during stable state and exacerbations of COPD

• Published in: The European respiratory journal Vol. 43; no. 1; pp. 64 - 71
• Main Authors: Bafadhel, Mona, Mckenna, Susan, Agbetile, Joshua, Fairs, Abbie, Desai, Dhananjay, Mistry, Vijay, Morley, Joseph P., Pancholi, Mitesh, Pavord, Ian D., Wardlaw, Andrew J., Pashley, Catherine H., Brightling, Christopher E.
• Format: Journal Article
• Language: English
• Published: Leeds Maney 01.01.2014
• Subjects: Adult; Aged; Aspergillosis - complications; Aspergillosis - immunology; Aspergillosis - microbiology; Aspergillus fumigatus - immunology; Aspergillus fumigatus - isolation & purification; Biological and medical sciences; Case-Control Studies; Chronic obstructive pulmonary disease, asthma; Disease Progression; Female; Forced Expiratory Volume; Humans; Immunoglobulin E - immunology; Male; Medical sciences; Middle Aged; Pneumology; Pulmonary Disease, Chronic Obstructive - complications; Pulmonary Disease, Chronic Obstructive - microbiology; Pulmonary Disease, Chronic Obstructive - physiopathology; Sputum - cytology; Sputum - microbiology; Fungi; Lung disease; Chronic; Respiratory disease; Bronchus disease; Chronic obstructive pulmonary disease; Fungi Imperfecti; Obstructive pulmonary disease; Aspergillus fumigatus

Bacteria are often isolated in stable chronic obstructive pulmonary disease (COPD). Whether fungi are also commonly present and associated with clinical and pathological features of disease is uncertain. We investigated the frequency of filamentous fungal culture and IgE sensitisation to Aspergillus...