Carcinogen: DNA adducts in tobacco smoke-associated cancer of the upper respiratory tract

• Published in: Acta biochimica polonica Vol. 46; no. 2; pp. 275 - 287
• Main Authors: Szyfter, K, Banaszewski, J, Jałoszyński, P, Pabiszczak, M, Szyfter, W, Szmeja, Z
• Format: Journal Article
• Language: English
• Published: Poland 01.01.1999
• Subjects: Carcinogens - toxicity; DNA Adducts - metabolism; Humans; Laryngeal Neoplasms - metabolism; Mouth Neoplasms - metabolism; Nicotiana; Plants, Toxic; Risk Factors; Smoking - adverse effects

Mortality connected with tobacco smoke-associated laryngeal cancer in Poland markedly exceeds the relevant epidemiological data from other European countries. The main groups of genotoxic agents considered as potential carcinogens present in tobacco smoke are polycyclic aromatic hydrocarbons, aromat...