Molecular, cellular, and muscle strip mechanics of the mdx mouse diaphragm

Duchenne muscular dystrophy (DMD) is a lethal disorder caused by defects in the dystrophin gene, which leads to respiratory or cardiac muscle failure. Lack of dystrophin predisposes the muscle cell sarcolemmal membrane to mechanical damage. However, the role of myosin in this muscle weakness has bee...

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Bibliographic Details
Published inAmerican Journal of Physiology: Cell Physiology Vol. 304; no. 9; pp. C873 - C880
Main Authors Bates, Genevieve, Sigurdardottir, Sara, Kachmar, Linda, Zitouni, Nedjma B, Benedetti, Andrea, Petrof, Basil J, Rassier, Dilson, Lauzon, Anne-Marie
Format Journal Article
LanguageEnglish
Published United States American Physiological Society 01.05.2013
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