Finger sweating levels evaluated by video capillaroscopy system are increased in patients with systemic sclerosis compared to pre-clinical stage patients

• Published in: Drug Discoveries & Therapeutics Vol. 14; no. 6; pp. 325 - 329
• Main Authors: Jinnin, Masatoshi, Tani, Sayaka, Mikita, Naoya, Fujii, Takao, Furukawa, Kanako, Tabata, Kayoko, Okuhira, Hisako
• Format: Journal Article
• Language: English
• Published: Japan International Research and Cooperation Association for Bio & Socio-Sciences Advancement 31.12.2020
• Subjects: Adult; Aged; capillaroscopy; Case-Control Studies; collagen; DNA Topoisomerases, Type I - metabolism; Early Diagnosis; Female; Fingers - physiology; Humans; Japan; Male; Microscopic Angioscopy - methods; Middle Aged; Scleroderma, Systemic - diagnostic imaging; Scleroderma, Systemic - metabolism; skin; sweat; Sweating; systemic sclerosis; topoisomerase I antibody; Japan; collagen; skin; sweat; capillaroscopy; systemic sclerosis; topoisomerase I antibody

New strategies for early diagnosis and careful follow-up of systemic sclerosis are urgently needed. We unconventionally used a video capillaroscopy system to measure the amount of sweating on finger pads, and investigated its clinical significance. Thirty-three Japanese patients who were diagnosed w...