Low Referral Rates for Genetic Assessment of Patients With Multiple Adenomas in United Kingdom Bowel Cancer Screening Programs

• Published in: Diseases of the colon & rectum Vol. 64; no. 9; pp. 1058 - 1063
• Main Authors: Alexander, James L., Johnston, Belinda J., Smith, Tom J., Yong, Karl King, Marshall, Sarah M., Fawkes, Jonathan D.C., Martin, John P., Seward, Edward W., Saunders, Brian, Monahan, Kevin J.
• Format: Journal Article
• Language: English
• Published: 01.09.2021

BACKGROUND: Approximately 1 in 20 cases of colorectal cancer are caused by monogenic syndromes. Published guidelines recommend that patients with 10 or more adenomas be referred for genetic testing, based on evidence that colorectal cancer risk is associated with adenoma multiplicity. OBJECTIVE: The...