Environment-sensitive hydrogels for drug delivery

• Published in: Advanced drug delivery reviews Vol. 64; pp. 49 - 60
• Main Authors: Qiu, Yong, Park, Kinam
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier B.V 01.12.2012; Elsevier
• Subjects: Biological and medical sciences; Drug delivery; Environment-sensitive hydrogels; General pharmacology; Medical sciences; Pharmaceutical technology. Pharmaceutical industry; Pharmacology. Drug treatments; Smart hydrogels; Stimuli-sensitive hydrogels; DMAEM; PLA; PMA; IPN; poly(acrylic acid); Con A; Stimuli-sensitive hydrogels; Drug delivery; PPO; PNIAAm; PEG; BMA; PAAm; PDEAEM; PVA; LCST; PEO; Environment-sensitive hydrogels; Smart hydrogels; PDEAAm; PVD; Colloidal gel; Pharmaceutical technology; Dosage form; Environment; Drug carrier; Hydrogel

Environmentally sensitive hydrogels have enormous potential in various applications. Some environmental variables, such as low pH and elevated temperatures, are found in the body. For this reason, either pH-sensitive and/or temperature-sensitive hydrogels can be used for site-specific controlled dru...