Probing Cell Mechanics with Bead-Free Optical Tweezers in the Drosophila Embryo

• Published in: Journal of visualized experiments no. 141
• Main Authors: Chardès, Claire, Clement, Raphael, Blanc, Olivier, Lenne, Pierre-François
• Format: Journal Article
• Language: English
• Published: United States JoVE 02.11.2018
• Subjects: Animals; Drosophila - embryology; Embryonic Development - physiology; Life Sciences; Optical Tweezers - therapeutic use

Morphogenesis requires coordination between genetic patterning and mechanical forces to robustly shape the cells and tissues. Hence, a challenge to understand morphogenetic processes is to directly measure cellular forces and mechanical properties in vivo during embryogenesis. Here, we present a set...