Principles for minimizing oxygen debt: can they translate to clinical application and improve outcomes?

• Published in: Best practice & research. Clinical anaesthesiology Vol. 35; no. 4; pp. 543 - 549
• Main Author: Maheshwari, Kamal
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01.12.2021
• Subjects: goal-directed therapy; oxygen debt; oxygen delivery; oxygen delivery; goal-directed therapy; oxygen debt

Oxygen delivery is dependent on pulmonary gas exchange, cardiac output, blood oxygen-carrying capacity, and tissue oxygen extraction. Reduction in oxygen delivery or higher oxygen consumption can initiate complex protective cellular processes precipitating oxygen debt. In critically ill and potentia...