Label-free surface-enhanced Raman spectroscopy for diagnosis and analysis of serum samples with different types lung cancer

• Published in: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy Vol. 261; p. 120021
• Main Authors: Lei, Jia, Yang, Dafu, Li, Rui, Dai, ZhaoXia, Zhang, Chenlei, Yu, Zhanwu, Wu, Shifa, Pang, Lu, Liang, Shanshan, Zhang, Yi
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 15.11.2021
• Subjects: PCA; PLS-DA; Serum; Silver nanoparticles; Surface-enhanced Raman spectroscopy; Serum; PLS-DA; Silver nanoparticles; Surface-enhanced Raman spectroscopy; PCA

[Display omitted] •Surface-enhanced Raman spectroscopy is useful for early detection of lung cancer.•PLS-DA was superior to PCA in the classification of lung cancer and normal subjects.•PLS-DA model could not completely separate the three types of lung cancer. Screening and detection of early lung c...