Target controlled alternative hybridization chain reaction for fluorescent detection of dual mycotoxins

• Published in: Analytica chimica acta Vol. 1237; p. 340595
• Main Authors: Ma, Qin, Lin, Yiyan, Yang, Yun, Yang, Wenming, Yun, Wen, Zhang, Mingming, Yang, Lizhu
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 02.01.2023
• Subjects: Aflatoxin B1; DNA tweezer; Hybridization chain reaction; Mycotoxin; Ochratoxin A; Aflatoxin B1; Hybridization chain reaction; DNA tweezer; Ochratoxin A; Mycotoxin

A target controlled alternative hybridization chain reaction (HCR) was developed for fluorescent detection of multiple mycotoxin. Ochratoxin A (OTA) and aflatoxin B1 (AFB1) can bind with their specific aptamer on the gold nanoparticles and cause the releasing of the short DNA sequences. The short DN...