Impact of Truncated Area on Point Estimate and Intra-Subject Variability in Bioequivalence of Dutasteride with Long Half-Life

• Published in: Drug research Vol. 68; no. 4; p. 238
• Main Authors: Prasaja, Budi, Harahap, Yahdiana, Lusthom, Windy, Yumi, Lia, Sofiana, Anna, Sandra, Monica, Safira, Falah, Chilmi, Uci
• Format: Journal Article
• Language: English
• Published: Germany 01.04.2018

To investigate the effect of using truncated area under the curve (AUC ) on bioequivalence of dutasteride with long half-life in point estimate and intra-subject variability. Fifteen subjects were enrolled in this single-dose, open-label, randomized two-way crossover design following an overnight fa...