Aerobic oxidation at benzylic positions catalyzed by a simple Pd(OAc) 2 /bis-triazole system

• Published in: RSC advances Vol. 5; no. 125; pp. 103210 - 103217
• Main Authors: Urgoitia, Garazi, Maiztegi, Ainhoa, SanMartin, Raul, Herrero, María Teresa, Domínguez, Esther
• Format: Journal Article
• Language: English
• Published: 01.01.2015
• Subjects: Aromatic compounds; Carbon; Carbonyls; Derivatives; Ligands; Oxidation; Oxygen; Palladium

An efficient catalyst system for the Pd-catalyzed aerobic oxidation of benzylic positions has been developed. The combination of palladium( ii ) acetate and 3,5-bis((1 H -1,2,4-triazol-1-yl)methyl)benzoate ligand allows the selective oxidation at carbon adjacent to arene rings (primary and secondary...