Periodontitis exacerbates the renal degenerative effects of obesity in rats

• Published in: Journal of periodontal research Vol. 56; no. 6; pp. 1058 - 1069
• Main Authors: Kurt‐Bayrakdar, Sevda, Kose, Oğuz, Altin, Ahmet, Akyildiz, Kerimali, Mercantepe, Tolga, Bostan, Semih Alperen, Kose, Taha Emre, Tumkaya, Levent, Yilmaz, Adnan
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc 01.12.2021
• Subjects: Alveolar bone; Antioxidants; Apoptosis; Bone loss; Caspase; Cathepsin D; Computed tomography; Creatinine; Cystatin C; Dentistry; Glutathione; Gum disease; immunohistochemistry; inflammation; Inflammatory diseases; kidney; Kidneys; Light microscopy; Matrix metalloproteinase; Metalloproteinase; Obesity; Oxidants; Oxidative stress; Periodontitis; Renal function; Silk; Statistical analysis; Structure-function relationships; Tumor necrosis factor; Tumor necrosis factor-TNF

Background/objectives Obesity and periodontitis are systemic subclinical inflammatory diseases with established negative renal effects. The aim of this animal study was to thoroughly investigate the possible effects of these two diseases on renal structure and function. Methods Thirty‐two male Sprag...