Imaging identification of primary mammary analogue secretory carcinoma and acinic cell carcinoma in major salivary glands

• Published in: Oral diseases Vol. 28; no. 7; pp. 1861 - 1870
• Main Authors: Ding, AngAng, Zuo, Jiaxin, Lv, Huan, Zhou, Lu, Ding, Shiwen, Yu, Qian, Xiong, Ping
• Format: Journal Article
• Language: English
• Published: Malden Wiley Subscription Services, Inc 01.10.2022
• Subjects: acinic cell carcinoma; Cancer; Computed tomography; Lymph nodes; Magnetic resonance imaging; mammary analogue secretory carcinoma; Salivary gland; Statistical analysis; ultrasonography; United States > US
• DOI: 10.1111/odi.14080
• ISSN: 1354-523X; 1601-0825

Objective The present study aimed to characterize and differentiate the ultrasonography (US) and computed tomography (CT) features of mammary analogue secretory carcinoma (MASC) and acinic cell carcinoma (AciCC). Methods and patients A total of 83 patients with clinically proven MASC and AciCC were analyzed. The following characteristics were assessed on US, CT, and magnetic resonance imaging: lesion size, shape, margin, echogenicity, echotexture, cystic components, posterior echo, vascularity, density, degree of enhancement, enhancement pattern, signal intensity (SI) on T1‐ and T2‐weighted images (WI), hemorrhages, and lymph node enlargement. Results Similarities were observed between the imaging performance of MASC and AciCC. Differences between the two characteristics of shape on US and cystic components on CT were statistically significant. The proportion of MASC to regular shape on US (p = 0.006) and cystic components on CT (p = 0.027) was significantly higher than that of AciCC. Regular shape on US had the highest sensitivity in the identification of MASC and AciCC, while regular shape on US + cystic component on CT had the highest specificity. Conclusions The shape on US and cystic components on CT are key characteristics for distinguishing MASC and AciCC.