Effects of dietary proline on swim bladder collagen synthesis and its possible regulation by the TGF‐β/Smad pathway in spotted drum, Nibea diacanthus

• Published in: Aquaculture nutrition Vol. 26; no. 5; pp. 1792 - 1805
• Main Authors: Rong, Hua, Lin, Fan, Limbu, Samwel Mchele, Lin, Zhideng, Bi, Baoliang, Dou, Tengfei, Zhao, Lei, Wen, Xiaobo
• Format: Journal Article
• Language: English
• Published: Oxford John Wiley & Sons, Inc 01.10.2020
• Subjects: Amino acids; blood serum; cluster analysis; Collagen; collagen synthesis; crude protein; Diet; dietary supplements; Drum; Fish; gene expression regulation; gene overexpression; Genes; Growth factors; human health; Liver; Metabolism; mothers against decapentaplegic homolog proteins; muscles; Nibea; Nibea diacanthus; procollagen-proline dioxygenase; Proline; Proteins; Protonibea diacanthus; Serum; signal transduction; Swim bladder; TGF‐β/Smad; tissues; transforming growth factor beta

Swim bladder is an ideal source of collagen production in fish for improved human health. Proline (Pro) is the main proteinogenic amino acid needed for collagen production. However, the effects of Pro supplementation on the swim bladder collagen synthesis have rarely been evaluated in fish. We deter...