Comprehensive SHAP Values and Single-Cell Sequencing Technology Reveal Key Cell Clusters in Bovine Skeletal Muscle

• Published in: International journal of molecular sciences Vol. 26; no. 5; p. 2054
• Main Authors: Guo, Yaqiang, Ma, Fengying, Li, Peipei, Guo, Lili, Liu, Zaixia, Huo, Chenxi, Shi, Caixia, Zhu, Lin, Gu, Mingjuan, Zhang, Wenguang
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.03.2025; MDPI
• Subjects: Accuracy; Animals; B cells; Cattle; Cells; Data models; Deep learning; Gene Expression Profiling; Genes; Machine learning; Muscle, Skeletal - cytology; Muscle, Skeletal - metabolism; Muscles; Musculoskeletal system; Neutrophils; Rankings; Single-Cell Analysis - methods; Swine; single-cell RNA-sequencing; SHAP; cattle; machine learning; skeletal muscles

The skeletal muscle of cattle is the main component of their muscular system, responsible for supporting and movement functions. However, there are still many unknown areas regarding the ranking of the importance of different types of cell populations within it. This study conducted in-depth researc...