MEMBRANPOTENTIAL AN DER NIERENTUBULI DES TRITURUS PYRRHOGASTER

An den tubulären Zellen des Triturus pyrrhogaster wurden sowohl das transmembrane als auch das transtubuläre Potential gemessen. Die proximalen Tubulizellen ergaben ein transmembranes Potential von ca. 65 mV und ein transtubuläres Potential von 0-20 mV. Die distalen Tubuli zeigten ungefähr das gleic...

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Published inJapanese journal of pharmacology Vol. 11; no. 1; pp. 65 - 71
Main Authors SAKAI, FUMINORI, HOSHP, TAKESHI, HAGA, MIGHINOBU, ENOMOTO, YOSHIKAZU
Format Journal Article
LanguageEnglish
Published The Japanese Pharmacological Society 01.01.1961
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Abstract An den tubulären Zellen des Triturus pyrrhogaster wurden sowohl das transmembrane als auch das transtubuläre Potential gemessen. Die proximalen Tubulizellen ergaben ein transmembranes Potential von ca. 65 mV und ein transtubuläres Potential von 0-20 mV. Die distalen Tubuli zeigten ungefähr das gleiche transmembrane Potential. Die Versuche, den Einfluss von Elektrolyten auf das Potential zu untersuchen, führten zu dem Ergebnis, dass beide Zellmembrane der proximalen Tubulizellen (peritubuläre und luminäre Membran) für Kalium-Ionen mehr permeabel als Natrium und Chlorid sind. Nach Applikation von Salyrgan wurde keine Veränderung des transmembranen Potentials beobachtet, obwohl Salyrgan eine diuretische Wirkung zeigte.
AbstractList An den tubulären Zellen des Triturus pyrrhogaster wurden sowohl das transmembrane als auch das transtubuläre Potential gemessen. Die proximalen Tubulizellen ergaben ein transmembranes Potential von ca. 65 mV und ein transtubuläres Potential von 0-20 mV. Die distalen Tubuli zeigten ungefähr das gleiche transmembrane Potential. Die Versuche, den Einfluss von Elektrolyten auf das Potential zu untersuchen, führten zu dem Ergebnis, dass beide Zellmembrane der proximalen Tubulizellen (peritubuläre und luminäre Membran) für Kalium-Ionen mehr permeabel als Natrium und Chlorid sind. Nach Applikation von Salyrgan wurde keine Veränderung des transmembranen Potentials beobachtet, obwohl Salyrgan eine diuretische Wirkung zeigte.
Author HAGA, MIGHINOBU
HOSHP, TAKESHI
SAKAI, FUMINORI
ENOMOTO, YOSHIKAZU
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CitedBy_id crossref_primary_10_1038_ki_1976_14
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crossref_primary_10_1007_BF00362656
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Cites_doi 10.1113/jphysiol.1958.sp006058
10.1152/ajplegacy.1958.194.1.135
10.1002/jcp.1030510208
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References 3) MARVIN, R.L., WILDE, W.S. UND SULLIVAN, L.P. : Localization of nephron transport by stop flow analysis Amer. J. Physiol. 194,135 (1958
2) SMITH, H.W. : The kidney; Structure and Function in Health and Disease, Oxford Univ. Press, N.Y. (1951
11) ELLINGER, PH. UND HIRT, A. : Mikroskopische Untersuchungen an lebenden Organ Ibid. 150,285 (1930
4) RICHARDS, A.N. UND WALKER, A.M. : Methods of collecting fluid from known regions of the renal tubules of amphibia and of perfusing the lumen of a single tubule Ibid. 118,111 (1937
1) EIGLER, F.W. : Methode zur Messung von Transportvorgängen in einzelnen Nierentubuli, Nieren Symposion, Georg Thieme Verlag, Stuttgart (1960
7) GIEBISCH, G. : Measurements of Electrical Potentials and Ion Fluxes on Single Renal Tubules, Nieren Symposion, Georg Thieme Verlag, Stuttgart (1960
8) GIEBISCH, G. : Electrical potential measurements on single nephrons of Necturus J. cell. comp. Physiol. 51,221 (1958
6) WEARN, J.T. UND RICHARDS, A.N. : Observations on the composition of glomerular urine, with particular reference to the problem of reabsorption in the renal tubules Ibid. 71,209 (1924
5) SHIPP, J.C., HANENSON, I.B., WINDHAGER, E.E., SCHATZMANN, H.J., WHITTEMBURG, G., YOSHIMURA, H. UND SOLOMON, A.K. : Single proximal tubules of the Necturus kidney. Methods of micropuncture and microperfusion Ibid. 195,563 (1958
12) GIEBISCH, G. : Measurements of electrical potential differences on single nephrons of the perfused Necturus kidney J. gen. Physiol. 44, 1 (1961
13) MAIZELS, M. UND REMINGTON, M. : Mercaptomerin and water exchange in cortex slices of rat kidney J. Physiol. 143,275 (1958
9) SOLOMON, A.K. : Ion and Water Transport in Single Proximal Tubules of the Necturus Kidney; The Method of Isotopic Tracers Applied to the Study of Active Ion Transport, Pergamon Press (1959
10) SAKAI, F., ENOMOTO, Y. UND HAGA, M. : Arch. exp. Path. Pharmak. 242,430 (1962
Solomon (10.1254/jjp.11.65_bib9) 1959
Giebisch (10.1254/jjp.11.65_bib7) 1960
Ellinger (10.1254/jjp.11.65_bib11) 1930; 150
Giebisch (10.1254/jjp.11.65_bib8) 1958; 51
Richards (10.1254/jjp.11.65_bib4) 1937; 118
Marvin (10.1254/jjp.11.65_bib3) 1958; 194
Eigler (10.1254/jjp.11.65_bib1) 1960
Wearn (10.1254/jjp.11.65_bib6) 1924; 71
Maizels (10.1254/jjp.11.65_bib13) 1958; 143
Smith (10.1254/jjp.11.65_bib2) 1951
Sarai (10.1254/jjp.11.65_bib10) 1962; 242
Giebisch (10.1254/jjp.11.65_bib12) 1961; 44
Shipp (10.1254/jjp.11.65_bib5) 1958; 195
References_xml – year: 1960
  ident: 10.1254/jjp.11.65_bib1
  contributor:
    fullname: Eigler
– year: 1951
  ident: 10.1254/jjp.11.65_bib2
  contributor:
    fullname: Smith
– volume: 242
  start-page: 430
  year: 1962
  ident: 10.1254/jjp.11.65_bib10
  publication-title: Arch. exp. Path. Pharmak.
  contributor:
    fullname: Sarai
– volume: 44
  start-page: 1
  year: 1961
  ident: 10.1254/jjp.11.65_bib12
  article-title: Measurements of electrical potential differences on single nephrons of the perfused
  publication-title: Necturus kidney J. gen. Physiol.
  contributor:
    fullname: Giebisch
– volume: 195
  start-page: 563
  year: 1958
  ident: 10.1254/jjp.11.65_bib5
  article-title: Single proximal tubules of the Necturus kidney. Methods of micro-puncture and microperfusion
  publication-title: Ibid.
  contributor:
    fullname: Shipp
– year: 1959
  ident: 10.1254/jjp.11.65_bib9
  contributor:
    fullname: Solomon
– volume: 150
  start-page: 285
  year: 1930
  ident: 10.1254/jjp.11.65_bib11
  article-title: Mikroskopische Untersuchungen an lebenden Organ
  publication-title: Ibid.
  contributor:
    fullname: Ellinger
– volume: 71
  start-page: 209
  year: 1924
  ident: 10.1254/jjp.11.65_bib6
  article-title: Observations on the composition of glomerular urine, with particular reference to the problem of reabsorption in the renal tubules
  publication-title: Ibid.
  contributor:
    fullname: Wearn
– volume: 143
  start-page: 275
  year: 1958
  ident: 10.1254/jjp.11.65_bib13
  article-title: Mercaptomerin and water exchange in cortex slices of rat kidney
  publication-title: J. Physiol.
  doi: 10.1113/jphysiol.1958.sp006058
  contributor:
    fullname: Maizels
– volume: 194
  start-page: 135
  year: 1958
  ident: 10.1254/jjp.11.65_bib3
  article-title: Localization of nephron transport by stop flow analysis
  publication-title: Amer. J. Physiol.
  doi: 10.1152/ajplegacy.1958.194.1.135
  contributor:
    fullname: Marvin
– volume: 118
  start-page: 111
  year: 1937
  ident: 10.1254/jjp.11.65_bib4
  article-title: Methods of collecting fluid from known regions of the renal tubules of amphibia and of perfusing the lumen of a single tubule
  publication-title: Ibid.
  contributor:
    fullname: Richards
– year: 1960
  ident: 10.1254/jjp.11.65_bib7
  contributor:
    fullname: Giebisch
– volume: 51
  start-page: 221
  year: 1958
  ident: 10.1254/jjp.11.65_bib8
  article-title: Electrical potential measurements on single nephrons of
  publication-title: Necturus J. cell. comp. Physiol.
  doi: 10.1002/jcp.1030510208
  contributor:
    fullname: Giebisch
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