Lack of Elevated Expression of TGFβ3 Contributes to the Delay of Epithelial Wound Healing in Diabetic Corneas

• Published in: Investigative ophthalmology & visual science Vol. 65; no. 3; p. 35
• Main Authors: Gao, Nan, Yu, Fu-Shin
• Format: Journal Article
• Language: English
• Published: United States 05.03.2024
• Subjects: Animals; Cornea; Corneal Injuries; Diabetes Mellitus, Experimental; ErbB Receptors; Humans; Hyperglycemia; Mice; Mice, Inbred C57BL; Transforming Growth Factor beta3 - genetics

To investigate the mechanisms underlying the differential roles of TGFβ1 and TGFβ3 in accelerating corneal epithelial wound healing (CEWH) in diabetic (DM) corneas, with normoglycemia (NL) corneas as the control. Two types of diabetic mice, human corneal organ cultures, mouse corneal epithelial prog...