Vitamin E supplementation increases LDL resistance to ex vivo oxidation in hemodialysis patients

• Published in: International journal for vitamin and nutrition research Vol. 73; no. 4; p. 290
• Main Authors: Badiou, Stephanie, Cristol, Jean-Paul, Morena, Marion, Bosc, Jean-Yves, Carbonneau, Marie-Annette, Dupuy, Anne-Marie, Descomps, Bernard, Canaud, Bernard
• Format: Journal Article
• Language: English
• Published: Switzerland 01.07.2003
• Subjects: Analysis of Variance; Arteriosclerosis - blood; Arteriosclerosis - metabolism; Arteriosclerosis - prevention & control; Chromatography, High Pressure Liquid; Chronic Disease; Dietary Supplements; Female; Follow-Up Studies; Humans; Lipid Metabolism; Lipids - blood; Lipoproteins, LDL - chemistry; Lipoproteins, LDL - drug effects; Lipoproteins, LDL - metabolism; Male; Middle Aged; Oxidation-Reduction - drug effects; Oxidative Stress - drug effects; Oxidative Stress - physiology; Prospective Studies; Renal Dialysis; Thiobarbituric Acid Reactive Substances - metabolism; Time Factors; Vitamin E - administration & dosage; Vitamin E - blood; Vitamin E - therapeutic use

Oxidative stress and alterations in lipid metabolism observed in hemodialysis patients potentiate the low-density lipoprotein (LDL) oxidability, recognized as a key event during early atherogenesis. To explore the effects of an oral vitamin E supplementation on oxidative stress markers and LDL oxida...