Effects of granulocyte-colony-stimulating factor and interleukin-2 on ascites formation and the survival time of nude mice bearing human ovarian cancer cells

• Published in: Cancer Immunology, Immunotherapy Vol. 43; no. 5; pp. 257 - 261
• Main Authors: KIKUCHI, Y, IMAIZUMI, E, KATAOKA, Y, HIRATA, J, KITA, T, TODE, T, NAGATA, I
• Format: Journal Article
• Language: English
• Published: Berlin Springer 01.12.1996; Springer-Verlag
• Subjects: Adjuvants, Immunologic - administration & dosage; Animals; Antineoplastic agents; Antineoplastic Agents - administration & dosage; Ascites; Biological and medical sciences; Chemotherapy; Cisplatin - administration & dosage; Female; Granulocyte Colony-Stimulating Factor - administration & dosage; Humans; Interleukin-2 - administration & dosage; Medical sciences; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Original; Ovarian Neoplasms - drug therapy; Pharmacology. Drug treatments; Transplantation, Heterologous; Intraperitoneal administration; Effusion; Treatment efficiency; Cytokine; Rodentia; Malignant tumor; Survival; Female genital diseases; Ovarian diseases; Ovary; Vertebrata; Chemotherapy; Granulocyte colony stimulating factor; Experimental disease; Mammalia; Interleukin 2; Mouse; Abdominal disease; Animal; Metastatic; Ascites

The aim of this study was to elucidate the effect of intraperitoneal (i.p.) instillations of granulocyte-colony-stimulating factor (G-CSF) and/or interleukin-2 (IL-2) on ascites formation and the survival time of nude mice with malignant ascites, produced by i.p. inoculation of human ovarian cancer...