Isolated coarctation of the aorta in the fetus: A diagnostic challenge
Isolated coarctation of the aorta (CoA) is estimated by the Centers for Disease Control and Prevention to account for 4%–6% of all congenital heart disease (CHD) in the United States, with a reported prevalence of ~4 per 10 000 live births. Prenatal recognition of coarctation is important as it may...
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Published in | Echocardiography (Mount Kisco, N.Y.) Vol. 34; no. 12; pp. 1768 - 1775 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
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01.12.2017
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Abstract | Isolated coarctation of the aorta (CoA) is estimated by the Centers for Disease Control and Prevention to account for 4%–6% of all congenital heart disease (CHD) in the United States, with a reported prevalence of ~4 per 10 000 live births. Prenatal recognition of coarctation is important as it may improve neonatal survival and reduce morbidity. However, despite advances in imaging and the trend toward detailed aortic arch assessment as part of a comprehensive fetal echocardiogram, isolated CoA may still elude prenatal detection, with potentially lethal consequences if the diagnosis is not suspected and the patent ductus arteriosus (PDA) closes spontaneously in postnatal life. The purpose of this review is to outline the methods of antenatal aortic arch evaluation in the current era, discuss “red flags” that raise the suspicion for CoA, including associated anomalies and serve as a repository of the most up to date information regarding its diagnosis in utero and its perinatal management. Other aortic arch abnormalities, such as interrupted aortic arch, or CoA associated with complex single ventricles, are not included in this review. |
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AbstractList | Isolated coarctation of the aorta (CoA) is estimated by the Centers for Disease Control and Prevention to account for 4%-6% of all congenital heart disease (CHD) in the United States, with a reported prevalence of ~4 per 10 000 live births. Prenatal recognition of coarctation is important as it may improve neonatal survival and reduce morbidity. However, despite advances in imaging and the trend toward detailed aortic arch assessment as part of a comprehensive fetal echocardiogram, isolated CoA may still elude prenatal detection, with potentially lethal consequences if the diagnosis is not suspected and the patent ductus arteriosus (PDA) closes spontaneously in postnatal life. The purpose of this review is to outline the methods of antenatal aortic arch evaluation in the current era, discuss "red flags" that raise the suspicion for CoA, including associated anomalies and serve as a repository of the most up to date information regarding its diagnosis in utero and its perinatal management. Other aortic arch abnormalities, such as interrupted aortic arch, or CoA associated with complex single ventricles, are not included in this review. Isolated coarctation of the aorta (CoA) is estimated by the Centers for Disease Control and Prevention to account for 4%–6% of all congenital heart disease (CHD) in the United States, with a reported prevalence of ~4 per 10 000 live births. Prenatal recognition of coarctation is important as it may improve neonatal survival and reduce morbidity. However, despite advances in imaging and the trend toward detailed aortic arch assessment as part of a comprehensive fetal echocardiogram, isolated CoA may still elude prenatal detection, with potentially lethal consequences if the diagnosis is not suspected and the patent ductus arteriosus ( PDA ) closes spontaneously in postnatal life. The purpose of this review is to outline the methods of antenatal aortic arch evaluation in the current era, discuss “red flags” that raise the suspicion for CoA, including associated anomalies and serve as a repository of the most up to date information regarding its diagnosis in utero and its perinatal management. Other aortic arch abnormalities, such as interrupted aortic arch, or CoA associated with complex single ventricles, are not included in this review. |
Author | Kailin, Joshua A. Yilmaz Furtun, Betul Santos, Alexia B. Lantin‐Hermoso, Regina Sexson Tejtel, S. Kristen |
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Cites_doi | 10.1002/pd.4498 10.1111/echo.13140 10.1097/MOP.0b013e32834382bd 10.1371/journal.pone.0065484 10.1016/j.echo.2004.04.011 10.1002/bdra.23111 10.1002/uog.12403 10.1038/srep39304 10.1002/uog.2597 10.1016/j.jtcvs.2009.11.075 10.1007/s00246-015-1168-7 10.1002/pd.4452 10.1002/ajmg.c.30131 10.1002/pd.4466 10.1161/CIRCULATIONAHA.116.024068 10.1111/chd.12405 10.1016/j.siny.2013.01.007 10.7863/ultra.15.06049 10.1002/uog.7483 10.1016/S0022-3468(98)90681-9 10.1542/peds.2015-1155 10.1542/peds.2004-1369 10.1002/uog.15914 10.1016/j.jpedsurg.2005.03.025 10.1002/uog.15846 10.7863/jum.2005.24.1.93 10.1016/j.athoracsur.2015.09.050 10.1002/uog.14882 10.1097/AOG.0000000000000015 10.1017/S1047951114001449 10.1016/j.acvd.2008.05.007 10.1161/01.cir.0000437597.44550.5d 10.1017/S104795111100196X 10.1002/uog.2605 10.1007/s00246-016-1520-6 10.1017/S1047951112000467 |
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Snippet | Isolated coarctation of the aorta (CoA) is estimated by the Centers for Disease Control and Prevention to account for 4%–6% of all congenital heart disease... Isolated coarctation of the aorta (CoA) is estimated by the Centers for Disease Control and Prevention to account for 4%-6% of all congenital heart disease... |
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SubjectTerms | Aorta - diagnostic imaging aorta coarctation Aortic Coarctation - diagnostic imaging echocardiography Echocardiography - methods Female fetal echocardiography Fetal Heart - diagnostic imaging Humans Pregnancy Ultrasonography, Prenatal - methods |
Title | Isolated coarctation of the aorta in the fetus: A diagnostic challenge |
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