Virological Profiles in Patients With Chronic Hepatitis C and Overt Or Occult Hbv Infection

• Published in: The American journal of gastroenterology Vol. 97; no. 6; pp. 1518 - 1523
• Main Authors: Squadrito, Giovanni, Orlando, Maria Elena, Pollicino, Teresa, Raffa, Giuseppina, Restuccia, Tea, Cacciola, Irene, Di Marco, Vito, Picciotto, Antonio, Colucci, Giuseppe, Craxì, Antonio, Raimondo, Giovanni
• Format: Journal Article
• Language: English
• Published: Oxford . 01.06.2002; Blackwell Publishing; Wolters Kluwer Health Medical Research, Lippincott Williams & Wilkins
• Subjects: Adult; Aged; Biological and medical sciences; DNA, Viral - blood; Female; Gastroenterology; Genome, Viral; Hepacivirus - genetics; Hepacivirus - physiology; Hepatitis B virus - genetics; Hepatitis B virus - physiology; Hepatitis B, Chronic - blood; Hepatitis B, Chronic - virology; Hepatitis C, Chronic - blood; Hepatitis C, Chronic - virology; Human viral diseases; Humans; Infectious diseases; Male; Medical sciences; Middle Aged; RNA, Viral - blood; Viral diseases; Viral hepatitis; Viral Load; Virus Replication; Human; Orthohepadnavirus; Hepatic disease; Cell cell interaction; Infection; Virus; Viral hepatitis B; Chronic; Hepadnaviridae; Viral disease; Digestive diseases; Severity score; Superinfection; Hepatitis B virus; Flaviviridae; Hepatitis C virus; Hepacivirus; Viral hepatitis C

The virological profiles of hepatitis B and C viruses (HBV and HCV) and their interplay in cases of coinfection are undefined. A suppressed and occult HBV infection may occur in hepatitis B surface antigen (HBsAg) negative patients with chronic hepatitis C. The HCV core protein is able to inhibit HB...