The Effect of Intraoperative Systemic Lidocaine on Postoperative Persistent Pain Using Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials Criteria Assessment Following Breast Cancer Surgery: A Randomized, Double‐Blind, Placebo‐Controlled Trial

• Published in: Pain practice Vol. 18; no. 3; pp. 350 - 359
• Main Authors: Kendall, Mark C., McCarthy, Robert J., Panaro, Steve, Goodwin, Emily, Bialek, Jane M., Nader, Antoun, De Oliveira, Gildasio S.
• Format: Journal Article
• Language: English
• Published: United States 01.03.2018
• Subjects: Administration, Intravenous; Adult; Analgesics, Opioid - therapeutic use; Anesthetics, Local - administration & dosage; Breast Neoplasms - surgery; breast surgery; Chronic Pain - epidemiology; Chronic Pain - prevention & control; Double-Blind Method; Female; Humans; IMMPACT criteria; Incidence; Intraoperative Care; lidocaine; Lidocaine - administration & dosage; Mastectomy - adverse effects; Middle Aged; Pain Measurement; Pain, Postoperative - epidemiology; Pain, Postoperative - prevention & control; persistent postoperative pain; Prospective Studies; IMMPACT criteria; persistent postoperative pain; breast surgery; lidocaine

Objective To compare the incidence in postsurgical persistent pain following breast cancer surgery in women receiving intravenous lidocaine compared to saline using validated pain instruments in accordance with the Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials (IMMPACT)...